Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms
نویسندگان
چکیده
منابع مشابه
Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms
During mammalian lung development, the morphological transition from respiratory tree branching morphogenesis to a predominantly saccular architecture, capable of air-breathing at birth, is dependent on physical forces as well as molecular signaling by a range of transcription factors including the cAMP response element binding protein 1 (Creb1). Creb1(-/-) mutant mice exhibit complete neonatal...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep25569